- In a separate bowl, whisk together the milk and ketchup until smooth and fully combined. This creates a tangy, creamy sauce that binds the casserole together and keeps the meatloaf moist as it bakes. Pour the mixture evenly over the top of the layered noodles and cheese.
- Bake the casserole uncovered for about 45 minutes, or until the meat is fully cooked and the top is bubbling and lightly browned. The internal temperature of the meat layer should reach at least 160°F (71°C) for food safety.
- Remove the dish from the oven and let it cool for 5–10 minutes before slicing and serving. This short resting period allows the casserole to firm up slightly for cleaner cuts and helps the flavors settle together.
Tips & Serving Suggestions
- Serve with a side salad or steamed green beans to round out the meal.
- For added flavor, mix in chopped onions, garlic, or herbs into the meatloaf layer before baking.
- Leftovers reheat well and make a satisfying lunch the next day—store covered in the refrigerator for up to 3 days.
This Mac and Cheese Meatloaf Casserole is the ultimate comfort food hybrid, combining two family favorites into one hearty, cheesy, oven-baked dish!
